Ask me how!!!

Jim Edwards, over at BNet, has noticed a change of tone in GSK’s blog for weight loss drug Alli.

Why does a drug need a blog anyway?

Sold as Xenical in Australia, Alli is a fairly notorious drug; it last made news here in 2006 when Xenical advertising run during Australian Idol was criticised for targeting teenage girls. A complaint from Choice Magazine very nearly cost the drug its over-the-counter status, and the TGA revoked Roche’s ability to advertise the drug direct to the consumer in Australia.

The marketer of the over-the-counter version of the drug in the US, GlaxoSmithKilne, have a blog devoted to the “wonders” of the drug. As Edwards points out, a change in sales management has lead to a very a distinct change of tone; away from a chatty style with a focus on health and nutrition (albeit with a strong sideline in “buy our drug”), and on to a much more aggressive “if you’re fat and ugly (you know—anything larger than a size 10), you’ll feel better if you take our drug.”

From a sales perspective, Xenical clearly has a problem - worldwide sales of around $40 million last quarter won’t even cover the advertising budget for the drug, let alone repay the substantial development costs.

That’s probably got a fair bit to do with the drug’s notorious “treatment” effects. Xenical works by blocking the absorption of fat in the stomach—so if the fat doesn’t get absorbed into the body…well…GSK advises you to wear dark pants when on the drug, and to keep a spare set of clothes around “just in case”.

Also, in order to avoid the unpleasant side-effects, you’re supposed to minimise your intake of fat while taking the drug (what doesn’t go in your mouth can’t stain your pants), which makes you wonder why they don’t save themselves and their poor customers some money and just replace the bloody thing with a sugar pill and a slightly different set of lies…

It will be interesting to see if the blog’s change in tone heralds a change in the marketing strategy across the board. I’m sure we all hope that the exciting new strategy of insulting women and their fat friends will lift sales of the drug for the asshats that sell it.

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8 Responses to “Ask me how!!!”


  1. 1 derrida deriderNo Gravatar

    My wife tried Xenical (she needed to lose weight on health, not fashion, grounds) and found it quite effective, just not in the way the makers claim. She says it’s simple behaviouralism - eating any fat quickly gets associated with unpleasantness. I reckon Clockwork Orange style electric shocks would be kinder.

    There’s no way it should be available over the counter, though. There are too many people neurotic about food as it is.

  2. 2 dannyNo Gravatar

    Sounds crude, but effective … could do the same thing for smoking? When you gave up, and took them as a no-return insurance policy, you’d only bust once I reckon.

  3. 3 HelenNo Gravatar

    I dunno… Here in Australia “low-fat” seems to have been elevated to a miraculous status whereas people seem to pay very little attention to the sugar content of anything! Therefore, I am constantly seeing “low-fat snacks” in the supermarket aisles the packaging of which doesn’t mention that the product is 90% sugar (but that’s OK, it’s not fat, innit?!), the same goes for the “low fat” version of things like yoghurt - they just taste like sweet syrup. then there are the RIDICULOUS examples of things like marshmallows and jelly sweets which were never meant to be marketed as health food, with “99% fat free!!!” on the packet. Of course they’re fat free - they’re made of sugar!

    I think a lot of the people buying the “low fat” or “fat free” stuff would be better off with a dollop of lovely plain full fat yoghurt, for instance, instead of a hideously sweet sugary carton of flavoured “low fat” yoghurt. And so on.

  4. 4 Jason SoonNo Gravatar

    Well put, Helen. There is a lot of solid science behind what you say and I would even go further.The ‘low fat but high sugar’ fad you have noted may actually be making things worse - not only is it less tasty but it’s harmful. Low carb diets have been found to be superior to low fat diets. This article is worth reading in full. Cut out refined carbs (which are not that tasty anyway - which would you rather have - bread or bacon?) and enjoy all the fat you want - eat tasty and eat well.

    http://women.timesonline.co.uk/tol/life_and_style/women/diet_and_fitness/article4523487.ece

    But some choice bits here:

    Advocates of FBCG (fat bad carbs good) believed that the big dietary change behind our new miseries was increased consumption of animal fats on the basis that, for early man, there were lots of vegetables and fruit lying around, but a good kill would be rare. Recent research, however, suggests that kills could be very large and our ancestors did not, as we do, carve out the best bits; they ate the whole animal. Their fat intake was, in fact, much higher than we thought.

    The truth is that the big dietary change was not fat but carbohydrate consumption. Agricultural settlement resulted in the cultivation of cereals and root vegetables. Bread, potatoes and rice became the staffs of life. The FBCG people didn’t think they were a problem: pound for pound, they contained fewer calories than meat. But what carbohydrates do is stop you burning fat, so the fat you do consume gets laid down in your arteries and on your stomach. It’s not the burger that bloats, it’s the bun.

    Furthermore, carbs become sugar in the body. In the case of refined carbs – white flour or sugar – the effect is instantaneous. “Some of these starches, as soon as they hit the saliva in your mouth, become sugars. Pasta is a bowl of sugar, briefly deferred.”

    This produces blood-sugar spikes that stress the pancreas and put millions in a pre-diabetic condition. They develop metabolic syndrome in which fat accumulates about the midriff and fundamentally alters body chemistry. This, it is thought, may well be either a primary or secondary cause of the diseases of modernity: cancers, heart attacks, strokes and, of course, all the woes that flow from obesity.

    Arthur is not alone in understanding the lethality of carbs. The whole FBCG ideology is now on the run. One very successful book, The Diet Delusion by Gary Taubes, exposed how threadbare the science behind the ideology actually was. A recent study in The New England Journal of Medicine seemed to show conclusively that a low-carb diet was a better way of losing weight than either a low-fat or a Mediterranean diet. It also showed it reduced bad cholesterol – a clear refutation of most orthodox dietary advice. The Palaeolithic diet, meanwhile, a regime based on the diet of early man, was first advocated in 1975. .

  5. 5 derrida deriderNo Gravatar

    I might add my wife’s regime did include a low GI approach - as, to be fair, Xenical’s makers advise in their blurb.

  6. 6 GWNo Gravatar

    low carb is the whole idea behind the atkins diet, right?

    you still have to cut out trans fats and lower the consumption of saturated fats though. and salt. and alcohol. and smoking. and cholesterol.

  7. 7 HelenNo Gravatar

    I’m not actually advocating a low carb diet which would be counterproductive to someone like me with a family history of colon cancer. I loves me carbs, rice, pasta mmmmm! I just don’t kid myself that a goopy mixture of fruit flavouring and corn syrup is good for me just because it contains very little “fat”.

  8. 8 DavidNo Gravatar

    I just can’t understand why anyone would ruin perfectly good yoghurt by removing all its fat, then adding fruit.

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